Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p340 | (1) | WCRB2014

Proteome-wide changes in liver function by continuous exposure to sewage sludge

Filis Panagiotis , Turner Emily Eaton , O'Shaughnessy Peter , Fowler Paul A

Introduction: A complex cocktail of poorly biodegradable chemicals is ubiquitous in the modern environment. Exposure to such chemicals contributes to diseases such as metabolic syndrome and infertility. Since the liver is the primary defence organ against xenotoxicants, we analysed the liver proteome of sheep continuously exposed (from pre-conception until early adulthood) to sewage sludge. Our aim was to identify dysregulated pathways and understand how a chemical cocktail ca...